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This study was performed to investigate the effects of aluminium treatment on renal damage in rats. Seventy five male Sprague-Dawley strains were divided into five groups; the control, 250 ppm AlCl₃ group, 500 ppm AlCl3 group, 250 ppm Al₂(SO₄)₃ group, 500 ppm Al₂(SO₄)₃ group and kept on the diet fur 2 weeks. The body weight gain was more increased in AlCl₃ treated of rats but decreased in Al₂(SO₄)₃, treated rats than the control, on based in histophysiological examination, in AlCl₃ treated group, thyrodization of kidney tubular lumen and interstitial inflammatory cell infiltration, abscess formation were demonstrated and in Al₂(SO₄)₃ treated animals destruction of glomeruli and necrosis in kidney cortex by inflammatory cells were shownd. On the other hand, blue-pigmented cast was noted in tubules of AlCl₃ administration group whereas focal aluminium accumulation was noted at interstitial tissue in kidney of Al₂(SO₄)₃ administration group.
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